… In Bioko, the N-terminus of pfcsp showed limited genetic variations and the numbers of … the
majority mutations located at T cell epitopes. Global genetic polymorphism and geographical …

… vivax in an endemic area of the Brazilian Amazon. … falciparum has been licensed, RTS,
S, which showed limited … IL-2 is mainly produced by activated T cells and it is important for …

… aimed to investigate the pvcsp polymorphisms in CR (286–… of pvcsp genetic diversity in
Brazil is limited since the majority of … Frequency of Plasmodium vivax circumsporozoite protein …

… Expression of Plasmodium falciparum circumsporozoite proteins in … Degenerate cytotoxic
T cell epitopes from P. … Genetic polymorphism and natural selection of circumsporozoite …

… You are using a browser version with limited support for CSS. … falciparum circumsporozoite
protein (PfCSP), present in the … the effect of parasite genetic polymorphisms in the immunity of …

… This vaccine is based on the Plasmodium falciparum circumsporozoite surface protein (…
limited genetic polymorphism in the P. vivax etramp11.2 gene in parasite populations from Brazil …

… variants are restricted to the central repeated region of the protein, … Polymorphism in the
IL-1β promoter is associated with IgG … to three species of plasmodium in the Brazilian Amazon. …

… contain polymorphic T cell … T cell epitopes within PfCSP has been slow due to the complexities
of human leukocyte antigen (HLA)-restriction and lack of tools to predict T cell epitopes. …

… Plasmodium falciparum and Plasmodium vivax are the most … the only Brazilian representative
from our protein portfolio, it … polymorphisms predominantly in regions of B cell epitopes of …

… PvCSP incorporating prevalent polymorphisms, adjuvanted … , its protection proved to be of
limited duration (6). Importantly, … for follicular helper T cells in mice immunized with a P. vivax …